TrxR-IN-4 is a thioredoxin reductase (TrxR) inhibitor with a rat IC50 of 0.37 µM. TrxR-IN-4 inhibits TrxR activity, elevates reactive oxygen species (ROS) and induces apoptosis. TrxR-IN-4 mediates endoplasmic reticulum stress and induces mitochondrial dysfunction. TrxR-IN-4 can be used for the research of hepatocellular carcinoma[1].
Molecular Weight:
796.40
CAS Number:
[2414906-32-2]
Formula:
C28H20AuF8N2O2P
Target:
Apoptosis,Reactive Oxygen Species (ROS),TrxR
Application Notes:
MCE Product type: Reference compound
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