microRNA-21-IN-1 (compound A7) is an efficient microRNA inhibitor. microRNA-21-IN-1 has antiproliferative activity against Hela and HCT-116 cells with IC50s of 5.5 µM and 2.8 µM respectively, as well as promotes apoptosis of Hela cells. microRNA-21-IN-1 upregulates the expression of microRNA-21 downstream functional targets (PTEN, EGR1 and SLIT2). microRNA-21-IN-1 can be used for researching anticancer[1].
Molecular Weight:
548.65
Purity:
98.03
CAS Number:
[2848720-31-8]
Formula:
C30H37FN6O3
Target:
Apoptosis,MicroRNA
Application Notes:
MCE Product type: Reference compound
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