VEGFR-2/BRAF-IN-1 (Compound 4b) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.049, 0.063 and 0.005 µM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-1 induces apoptosis and arrests the cell cycle mainly in the G1/S phase[1].
Molecular Weight:
642.50
Formula:
C26H20Cl2F3N5O3S2
Target:
Apoptosis,Raf,VEGFR
Application Notes:
MCE Product type: Reference compound
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