VEGFR-2/BRAF-IN-2 (Compound 4a) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.111, 0.089 and 0.071 µM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-2 induces apoptosis and arrests the cell cycle mainly in the G1 phase[1].
Molecular Weight:
608.05
Formula:
C26H21ClF3N5O3S2
Target:
Apoptosis,Raf,VEGFR
Application Notes:
MCE Product type: Reference compound
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