R-HP210 acts on the NF-kappaB mediated tethered transrepression function (IC50=3.80 µM). R-HP210 represses the LPS-induced transcription of a variety of proinflammatory genes such as IL-1beta, IL-6 and COX-2. R-HP210 does not induce the transactivation functions of Glucocorticoids (GCs)[1].
Molecular Weight:
421.54
Purity:
98.21
Formula:
C22H19N3O2S2
Target:
NF-kappaB
Application Notes:
MCE Product type: Reference compound
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