DNA-PK-IN-8 is a highly potent, selective and orally active DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 value of 0.8 nM. DNA-PK-IN-8 exhibits synergistic antiproliferative activity against a series of cancer cell lines and significantly suppresses HL-60 tumor growth, when using in combination with Doxorubicin[1].
Molecular Weight:
394.43
Purity:
99.74
CAS Number:
[2823369-81-7]
Formula:
C19H22N8O2
Target:
DNA-PK
Application Notes:
MCE Product type: Reference compound
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