Thalidomide (Standard) is the analytical standard of Thalidomide. This product is intended for research and analytical applications. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of 250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.
Molecular Weight:
258.23
Purity:
99.96
CAS Number:
[50-35-1]
Formula:
C13H10N2O4
Target:
Apoptosis,Autophagy,Ligands for E3 Ligase,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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