Thalidomide-d4 is a deuterium labeled Thalidomide. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2].
Molecular Weight:
262.26
Purity:
98.71
CAS Number:
[1219177-18-0]
Formula:
C13H6D4N2O4
Target:
Apoptosis,Autophagy,Ligands for E3 Ligase,Molecular Glues
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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