KS100 is a potent ALDH inhibitor with IC50s of 230, 1542, 193 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS100 shows antiproliferative and anticancer effects with low low toxic. KS100 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS10600 induces apoptosis and cell cycle arrest at the G2/M phase[1].
Molecular Weight:
564.09
Purity:
99.61
CAS Number:
[2408477-54-1]
Formula:
C17H14Br3N3O2S
Target:
Aldehyde Dehydrogenase (ALDH),Apoptosis
Application Notes:
MCE Product type: Reference compound
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