KS106 is a potent ALDH inhibitor with IC50s of 334, 2137, 360 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS106 induces apoptosis and cell cycle arrest at the G2/M phase[1].
Molecular Weight:
474.29
Purity:
99.87
CAS Number:
[2408477-50-7]
Formula:
C18H15BrF3N3O2S
Target:
Aldehyde Dehydrogenase (ALDH),Apoptosis
Application Notes:
MCE Product type: Reference compound
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