mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian alpha/beta-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].
Molecular Weight:
385.37
Purity:
98
CAS Number:
[2418576-06-2]
Formula:
C16H17F6NOS
Target:
Epoxide Hydrolase
Application Notes:
Reference compound
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