RET-IN-16 is a potent and selective RET inhibitor with IC50s of 3.98 nM, 8.42 nM, 15.05 nM, 7.86 nM, 5.43 nM and 8.86 nM for RET(WT), RET(M918T), RET(V804L), RET(V804M), RET-CCDC6 and RET-KIF5B, respectively. RET-IN-16 has anticancer effects[1].
Molecular Weight:
602.61
CAS Number:
[2259657-48-0]
Formula:
C31H29F3N8O2
Target:
RET
Application Notes:
Reference compound
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