JAK3-IN-11, CAS [[2412734-00-8]] Preis auf Anfrage

Product Overview

• Article Name: JAK3-IN-11, CAS [[2412734-00-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-146727
• Supplier Catalog Number: HY-146727
• Alternative Catalog Number: MCE-HY-146727-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

JAK3-IN-11 (Compound 12), a potent, noncytotoxic, irreversible, orally active JAK3 inhibitor with IC50 value of 1.7 nM, has excellent selectivity (>588-fold compared to other JAK isoforms), covalently bind to the ATP-binding pocket in JAK3. JAK3-IN-11 strongly inhibits JAK3-dependent signaling and T cell proliferation, is a promising tool for study autoimmune diseases[1].

Product Properties

• Molecular Weight: 401.46
• CAS Number: [2412734-00-8]
• Formula: C23H23N5O2
• Target: JAK

Application Notes

• Application Notes: Reference compound