CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC50=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities[1][2].
Molecular Weight:
469.55
Purity:
98.72
CAS Number:
[383432-38-0]
Formula:
C27H27N5O3
Target:
Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound
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