ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 µM and 1.372 µM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer[1].
Molecular Weight:
473.37
CAS Number:
[2415295-37-1]
Formula:
C19H17F6N7O
Target:
Apoptosis,PAK
Application Notes:
MCE Product type: Reference compound
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