EB1 is the inhibitor of kinases MNK with IC50s of 0.69 µM (MNK1) and 9.4 µM (MNK2). EB1 selectively inhibits the growth of cancer cells, but not normal cells. EB1 also increases cell apoptosis and suppresses eIF4E phosphorylation[1][2].
Molecular Weight:
286.33
Purity:
99.91
CAS Number:
[42951-68-8]
Formula:
C18H14N4
Target:
Apoptosis,Eukaryotic Initiation Factor (eIF),MNK
Application Notes:
MCE Product type: Reference compound1
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