CEP-8983 is a PARP-1 and PARP-2 inhibitor (IC50: 20 and 6 nM). CEP-8983 is an effective chemosensitizing agent, and can sensitize chemotherapy-resistant cell lines and subcutaneous xenografts to Temozolomide (HY-17364) and Camptothecin (HY-16560)[1].
Molecular Weight:
306.32
CAS Number:
[374071-46-2]
Formula:
C18H14N2O3
Target:
PARP
Application Notes:
MCE Product type: Reference compound
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