XP-524 is a potent BET and EP300 inhibitor. XP-524 shows great tumoricidal activity in vivo. XP-524 prevents KRAS-induced, neoplastic transformation in vivo and extends survival in two transgenic mouse models of aggressive PDAC. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes. XP-524 has the potential for the research of pancreatic ductal adenocarcinoma (PDAC)[1].
Molecular Weight:
552.65
Purity:
98.02
CAS Number:
[2344825-52-9]
Formula:
C30H28N6O3S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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