PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis[1].
Molecular Weight:
424.28
Purity:
99.48
CAS Number:
[684234-55-7]
Formula:
C22H15Cl2N3O2
Target:
Apoptosis,Caspase,PARP
Application Notes:
MCE Product type: Reference compound
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