Zedoresertib (Debio 0123) is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. Zedoresertib inhibits phospho-CDC2. Zedoresertib abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. Zedoresertib can be used for researching anticancer[1].
Molecular Weight:
511.45
Purity:
99.85
CAS Number:
[2243882-74-6]
Formula:
C26H28Cl2N6O
Target:
CDK,Wee1
Application Notes:
MCE Product type: Reference compound
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