dTAG-47 is a FKBP12F36V PROTAC degrader. dTAG-47 efficiently degrades FKBP12F36V-MELK(sg3R) in MELK^/^ MDA-MB-468-FKBP12F36V-MELK(sg3R) cells. dTAG-47 can be used for the research of basal-like breast cancers (BBC). (Pink: FKBP12F36V ligand (HY-114420), Blue: CRBN Ligand (HY-W087383), Black: Linker (HY-42773), E3 ligase ligand-linker conjugate (HY-175952))[1][2].
Molecular Weight:
1076.24
Purity:
99.65
CAS Number:
[2265886-81-3]
Formula:
C59H73N5O14
Target:
FKBP,PROTACs
Application Notes:
MCE Product type: Reference compound
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