JBJ-09-063, CAS [[2820336-67-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-147183
Supplier Catalog Number:
HY-147183
Alternative Catalog Number:
MCE-HY-147183-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
JBJ-09-063 is a mutant-selective allosteric EGFR inhibitor with IC50s of 0.147 nM, 0.063 nM, 0.083 nM and 0.396 nM for EGFR L858R, EGFR L858R/T790M, EGFR L858R/T790M/C797S and EGFRLT/L747S. JBJ-09-063 effectively reduces EGFR, Akt and ERK1/2 phosphorylation. JBJ-09-063 is effective across EGFR tyrosine kinase inhibitor (TKI)-sensitive and resistant models. JBJ-09-063 can be used for researching EGFR-mutant lung cancer[1].
Molecular Weight:
556.65
CAS Number:
[2820336-67-0]
Formula:
C31H29FN4O3S
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
