QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 µM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research[1].
Molecular Weight:
535.76
CAS Number:
[2754254-07-2]
Formula:
C33H49N3O3
Target:
HMG-CoA Reductase (HMGCR)
Application Notes:
MCE Product type: Reference compound
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