SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7alpha, 25-OHC-induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice[1].
Molecular Weight:
364.36
Purity:
98.60
CAS Number:
[1241280-25-0]
Formula:
C19H19F3N2O2
Target:
EBI2/GPR183
Application Notes:
MCE Product type: Reference compound
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