Elebsiran (VIR-2218) sodium is a siRNA that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. Elebsiran sodium leads to a significant decrease in HBV surface antigen (HBsAg) and a reduction in viral load. Elebsiran sodium binds to the sialic acid-depleted glycoprotein receptor (ASGPR) on the surface of liver cells through the GalNAc ligand, achieving liver-targeted delivery and demonstrating improved liver safety. Elebsiran sodium can be used for the study of chronic HBV/HDV infections[1][2][3].
Molecular Weight:
14976.67 (free acid)
Purity:
95.83
Formula:
C485H618F9N158Na40O294P39S6
Target:
HBV,Small Interfering RNA (siRNA)
Application Notes:
MCE Product type: Oligonucleotides
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