Izuforant (JW1601) (Compound 24) is an orally active histamine H4 receptor (H4R) antagonist with an IC50 of 36 nM against human H4R. Izuforant also shows binding affinity of human serotonin 3 receptor (h5-HT3R) with an IC50 of 9.1 µM. Izuforant exhibits strong anti-pruritic and anti-inflammatory efficacies[1][2].
Molecular Weight:
334.17
Purity:
98.88
CAS Number:
[1429374-83-3]
Formula:
C12H12BrN7
Target:
Histamine Receptor
Application Notes:
MCE Product type: Reference compound
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