Plogosertib (CYC140) is a selective, potent, and orally active ATP-competitive PLK1 inhibitor (IC50: 3 nM). Plogosertib is an anti-cancer agent with anti-proliferative activity. Plogosertib can be used in the research of several tumors, including esophageal, gastric, leukemia, non-small cell lung cancer, ovarian, and squamous cell cancers[1][2].
Molecular Weight:
616.80
Purity:
98.59
CAS Number:
[1137212-79-3]
Formula:
C34H48N8O3
Target:
Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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