NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 µM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research[1].
Molecular Weight:
375.11
Purity:
99.97
CAS Number:
[1912422-56-0]
Formula:
C13H8F2INO2
Target:
Nuclear Factor of activated T Cells (NFAT)
Application Notes:
MCE Product type: Reference compound
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