DA-PROTAC is a potent PROTAC degrader of copper ion-transport proteins Atox1 and CCS. DA-PROTAC can bind both Atox1 and CCS proteins, and the complex can be bound to E3 ligase, leading to increased levels of ubiquitination of Atox1 and CCS and degradation of Atox1 and CCS proteins via the proteasome pathway. DA-PROTAC can be used for triple negative breast cancer research[1].
Molecular Weight:
1010.96
CAS Number:
[2488660-12-2]
Formula:
C46H50BrF2N7O8S2
Target:
Ligands for E3 Ligase,PROTACs
Application Notes:
MCE Product type: Reference compound
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