Ultevursen (QR-421a) is a single-stranded RNA based oligonucleotide that is designed to skip exon 13 in the RNA with the aim to stop vision loss in people that have retinitis pigmentosa due to a mutation in exon 13 of the USH2A gene (encoding usherin). Ultevursen sequence: (P-thio)[2'-O-(2-methoxyethyl)](A-G-m5C-m5U-m5U-m5C-G-G-A-G-A-A-A-m5U-m5U-m5U-A-A-A-m5U-m5C)[1].
Molecular Weight:
8372.24
Purity:
94.24
CAS Number:
[2642382-41-8]
Formula:
C273H391N81O144P20S20
Target:
Nucleoside Antimetabolite/Analog
Application Notes:
MCE Product type: Oligonucleotides
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