Zifcasiran (sodium), CAS [[2437257-12-8]] Preis auf Anfrage
Catalog Number:
MCE-HY-147426A
| Article Name: |
Zifcasiran (sodium), CAS [[2437257-12-8]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-147426A |
| Supplier Catalog Number: |
HY-147426A |
| Alternative Catalog Number: |
MCE-HY-147426A-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| Alternative Names: |
ADS-007 (sodium), ARO HIF2 (sodium) |
| Zifcasiran (ADS-007) sodium is an siRNA synthetic double-stranded RNAi trigger. Zifcasiran sodium selectively target hypoxia-inducible factor-2alpha (HIF2alpha) interrupting downstream pro-oncogenic signaling in clear cell renal cell carcinoma (ccRCC). Zifcasiran sodium engages the cells RNAi machinery to target HIF2alpha (EPAS1) mRNA for degradation, thereby reducing the amount of free HIF2alpha mRNA available for translation[1]. |
| Molecular Weight: |
21491.26 |
| CAS Number: |
[2437257-12-8] |
| Formula: |
C737H929F20N211Na52O349P43S8 |
| Target: |
HIF/HIF Prolyl-Hydroxylase,Small Interfering RNA (siRNA) |
| Application Notes: |
MCE Product type: Oligonucleotides |