NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 µM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP)-induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-alpha release in PBMCs[1].
Molecular Weight:
474.57
Purity:
99.57
CAS Number:
[2411441-54-6]
Formula:
C26H26N4O3S
Target:
NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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