CB1/2 agonist 1 is a potent and cross the blood-brain barrier CB1/2 agonist with EC50s of 56.15, 11.63 nM for CB1R and CB2R, respectively. CB1/2 agonist 1 reduces glutamate release and LPS-induced activation of microglial cells. CB1/2 agonist 1 shows anti-inflammatory and antinociceptive effects. CB1/2 agonist 1 has the potential for the research of multiple sclerosis[1].
Molecular Weight:
435.33
Purity:
98.68
CAS Number:
[2986688-90-6]
Formula:
C21H24BrFN2O2
Target:
Cannabinoid Receptor
Application Notes:
MCE Product type: Reference compound
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