AKT-IN-12 (compound 3e) is a potent Akt kinase inhibitor with an IC50 value of 0.55 µM. AKT-IN-12 induces G0/G1 cell cycle arrest and apoptosis. AKT-IN-12 also inhibits p-AKT, p-ERK, and activates p-JNK, JNK. AKT-IN-12 can be used for researching leukemia[1].
Molecular Weight:
722.89
CAS Number:
[2396718-52-6]
Formula:
C42H46N2O7S
Target:
Akt,Apoptosis
Application Notes:
MCE Product type: Reference compound
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