Keap1-Nrf2-IN-9, CAS [[2769963-24-6]]

Product Overview

• Article Name: Keap1-Nrf2-IN-9, CAS [[2769963-24-6]]
• Biozol Catalog Number: MCE-HY-147517
• Supplier Catalog Number: HY-147517
• Alternative Catalog Number: MCE-HY-147517-5MG,MCE-HY-147517-25MG,MCE-HY-147517-100MG,MCE-HY-147517-10MMX1ML,MCE-HY-147517-10MG,MCE-HY-147517-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Keap1-Nrf2-IN-9 (Compound 11) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) inhibitor with an IC50 of 0.575 µM. Keap1-Nrf2-IN-9 increases the expression of Nrf2 target genes including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Keap1-Nrf2-IN-9 shows no cytotoxic activity in ARPE19 cells[1].

Product Properties

• Molecular Weight: 670.71
• Purity: 98.52
• CAS Number: [2769963-24-6]
• Formula: C31H30N2O11S2
• Target: Keap1-Nrf2

Application Notes

• Application Notes: MCE Product type: Reference compound