LSD1-IN-21 (compound 5a) is a potent and BBB-penetrated LSD1 (Lysine specific demethylase-1) inhibitor, with an IC50 of 0.956 µM. LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-alpha. LSD1-IN-21 shows good anticancer and anti-inflammatory activity[1].
Molecular Weight:
447.55
Formula:
C24H25N5O2S
Target:
Histone Demethylase,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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