PKC-IN-4 (compound 7l) is a potent and orally active aPKC inhibitor with an IC50 of 0.52 µM. PKC-IN-4 inhibits TNF-alpha induced NF-kappaB activity in vitro. PKC-IN-4 blocks VEGF- and TNFalpha-induced permeability across the retinal vasculature[1].
Molecular Weight:
379.52
CAS Number:
[2636771-29-2]
Formula:
C21H25N5S
Target:
PKC
Application Notes:
MCE Product type: Reference compound
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