Monepantel (AAD1566, NUZ-001), an antiparasitic agent, is an orally active mTOR inhibitor. Monepantel triggers autophagy through the deactivation of mTOR/p70S6K signalling pathway. Monepantel is a positive allosteric modulator of a nematode-specific clade of nAChR subunits. Monepantel can be used for the study of amyotrophic lateral sclerosis (ALS) and ovarian cancer[1][2][3][4].
Molecular Weight:
473.39
Purity:
99.98
CAS Number:
[887148-69-8]
Formula:
C20H13F6N3O2S
Target:
Autophagy,mTOR,nAChR,Parasite
Application Notes:
MCE Product type: Reference compound
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