Thi-DPPY (compound 8e) is a potent and orally active JAK3 inhibitor with IC50 values of 62.4, 1.38 nM for BTK, JAK, respectively. Thi-DPPY shows anti-proliferative activity against HBE cells. Thi-DPPY shows anti-inflammatory activity in vivo. Thi-DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF)[1].
Molecular Weight:
566.07
CAS Number:
[2307699-34-7]
Formula:
C28H28ClN5O4S
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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