Retosiban (GSK221149A) is a potent, selective, and orally active oxytocin receptor antagonist (Ki (hOT) = 0.65 nM, Ki (rOT) = 4.1 nM) with no detectable agonist activity. Retosiban has nanomolar affinity for the oxytocin receptor with >1400-fold selectivity over the closely related vasopressin receptors. Retosiban inhibits spontaneous and induces uterine contractions. Retosiban can be studied in research for preterm labour[1][2][4].
Molecular Weight:
494.58
Purity:
98.97
CAS Number:
[820957-38-8]
Formula:
C27H34N4O5
Target:
Oxytocin Receptor
Application Notes:
MCE Product type: Reference compound
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