Mimopezil (ZT-1) is an cholinesterase (ChE) inhibitor that rapidly degrades into the active metabolite Huperzine A (HY-17388) in water or aqueous organic solvents. After oral administration, Mimopezil is rapidly absorbed but has low bioavailability (0.37%) in rats. However, after metabolism, it is converted into Huperzine A, which accumulates in the blood and exhibits strong activity. Following intravenous administration, Mimopezil reaches higher blood concentrations and is also rapidly metabolized into Huperzine A[1].
Molecular Weight:
410.89
CAS Number:
[180694-97-7]
Formula:
C23H23ClN2O3
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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