I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Galphaq and Galpha12/13 activity and their downstream effectors. I-287 reduces Complete Freunds adjuvant (HY-153808)-induced inflammation in mice and can be used for inflammation/immunology research[1].
Molecular Weight:
565.04
Purity:
99.36
CAS Number:
[2014368-93-3]
Formula:
C30H30ClFN4O4
Target:
ERK,Protease Activated Receptor (PAR)
Application Notes:
MCE Product type: Reference compound
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