UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial beta-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 µM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes[1][2].
Molecular Weight:
411.52
Purity:
99.33
CAS Number:
[372495-52-8]
Formula:
C20H25N7OS
Target:
Bacterial,beta-glucuronidase
Application Notes:
MCE Product type: Reference compound1
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