Eplontersen is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases[1][2][3].
Molecular Weight:
8606.50
Purity:
96.92
CAS Number:
[1637600-16-8]
Target:
Transthyretin (TTR)
Application Notes:
MCE Product type: Oligonucleotides
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