TP-050, a chemical probe, is a potent, orally active and selective NMDAR agonist with an EC50 value of 0.51 µM and 9.6 µM for GluN2A and GluN2D, respecticely. TP-050 can cross the blood-brain barrier (BBB). TP-050 induces hippocampal long-term (LPT) potentiation enhancemen and enhances neuronal signal transmission[1].
Molecular Weight:
380.78
CAS Number:
[3085030-47-0]
Formula:
C16H15ClF2N6O
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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