KTX-582 is a potent IRAK4 degrader with DC50 values of 4 nM and 5 nM for IRAK4 and Ikaros, respectively. KTX-582 can induce apoptosis in MYD88MT DLBCL, and is efficient to induce in vivo tumor regressions in lymphoma model[1][2][3].
Molecular Weight:
872.93
Purity:
98.77
CAS Number:
[2573298-13-0]
Formula:
C45H51F3N8O7
Target:
Apoptosis,IRAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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