Aprinocarsen (ISIS 3521) sodium, a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-alpha). Aprinocarsen sodium is a 20-mer oligonucleotide, it regulates cell differentiation and proliferation. Aprinocarsen sodium inhibits the growth of human tumor cell lines in nude mice. Aprinocarsen sodium shows the value as a chemotherapeutic compound of human cancers[1].
Molecular Weight:
6435.2 (free acid)
Purity:
98.42
CAS Number:
[331257-53-5]
Formula:
C196H230N68Na19O105P19S19
Target:
PKC
Application Notes:
MCE Product type: Oligonucleotides
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