p53 Activator 7 is a p53 mutation Y220C (MDM-2/p53) activator with an EC50 of 104 nM. p53 Activator 7 can bind to p53 mutant and restore its ability to bind DNA (WO2022213975A1, Example B-1)[1]. p53 Activator 7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
516.54
Purity:
98.52
CAS Number:
[2849340-59-4]
Formula:
C27H32F3N4OP
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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