4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC50 of 1.5 µM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P45017alpha with an IC50 of 1600 nM, and also inhibits the 17alpha-hydroxylase activity of this enzyme with an IC50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer[1].
Molecular Weight:
270.37
Purity:
99.83
CAS Number:
[121768-39-6]
Formula:
C17H22N2O
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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