eIF4A3-IN-10 (compound 58) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-10 interferes the assembling of eIF4F translation complex with EC50s of 35 and 100 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-10 can be used for the research of human cancer pathogenesis[1].
Molecular Weight:
519.54
Purity:
97.87
CAS Number:
[1402931-72-9]
Formula:
C29H29NO8
Target:
Eukaryotic Initiation Factor (eIF)
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted